SCHEMBL9895088

SCHEMBL9895088

FC(F)(F)C(n1cncn1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.41
CYP3A4 P08684 2/20 0.35
CYP11B1 P15538 1/20 0.35
TSHR P16473 1/20 0.35
CYP11B2 P19099 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSP90AA1 P07900 3/20 0.34
CYP26A1 O43174 1/20 0.33
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7810598 0.72
SCHEMBL13555370 0.70 CYP19A1 (0.38) CYP19A1HSP90AA1KMT2AMAPTMEN1
SCHEMBL1371558 0.67
SCHEMBL23772083 0.67 CYP19A1 (0.41) CYP19A1CYP3A4CYP11B1TSHRCYP11B2
SCHEMBL2162413 0.67 CYP19A1 (0.42) CYP19A1CYP3A4CYP11B1TSHRCYP11B2
SCHEMBL10709771 0.65 MAPT (0.43) CYP19A1CYP3A4CYP2C19HSP90AA1CYP26A1
SCHEMBL9963220 0.63 CYP19A1 (0.42) CYP19A1CYP3A4CYP11B1TSHRCYP11B2
SCHEMBL22059457 0.63
SCHEMBL21165789 0.63 CYP19A1 (0.42) CYP19A1CYP3A4CYP11B1TSHRCYP11B2
SCHEMBL16323958 0.62 CYP19A1 (0.39) CYP19A1CYP3A4CYP11B1TSHRCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456759-B1 PESTICIDAL CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2017-04-19 EP disclosed
EP-3153497-A2 PESTICIDAL CARBOXAMIDES Bayer Cropscience AG (DE) 2017-04-12 EP disclosed
US-9227923-B2 Pesticidal carboxamides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-01-05 US disclosed
US-20120149910-A1 Pesticidal Carboxamides BAYER CROPSCIENCE AG (DE) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149910-A1 Pesticidal Carboxamides DDT, ACHE, AADAC CYP19A1 795/4885CYP3A4 772/4885CYP11B1 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.