⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079843 | 0.98 | CPN1 (0.70) | — | |
| SCHEMBL25389365 | 0.91 | CPN1 (0.68) | — | |
| SCHEMBL2353967 | 0.85 | CPN1 (1.00) | — | |
| SCHEMBL9063708 | 0.78 | — | — | |
| SCHEMBL2354051 | 0.78 | CPN1 (1.00) | — | |
| SCHEMBL3179113 | 0.77 | — | — | |
| SCHEMBL2349599 | 0.76 | CPN1 (1.00) | — | |
| SCHEMBL2352986 | 0.76 | CPN1 (1.00) | — | |
| Lithium Ion SCHEMBL4370616 | 0.76 | CPN1 (0.47) | — | |
| SCHEMBL11369626 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598781-B | Preparation method of key intermediate of montelukast sodium | 迪嘉药业集团股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-118598781-A | Preparation method of key intermediate of montelukast sodium | 迪嘉药业集团股份有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-114181121-B | Preparation method of 1-mercaptomethyl cyclopropylacetic acid | 江苏阿尔法药业股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-114591140-B | Montelukast sodium intermediate, preparation method thereof and preparation method using intermediate | 江苏阿尔法药业股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-116332816-A | Method for preparing 1-mercaptomethyl cyclopropylacetic acid by one-step method | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-113337857-B | Acidic sulfate copper electroplating combined additive for thickening PCB through hole metal | 厦门大学 | 2022-06-21 | — | — | CN | claimed |
| CN-113337857-A | Acidic sulfate copper electroplating combined additive for thickening PCB through hole metal | 厦门大学 | 2021-09-03 | — | — | CN | claimed |
| CN-112094212-A | Preparation method of montelukast sodium side chain | 宿迁盛基医药科技有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-20130045391-A1 | Tarnish Inhibiting Composition for Metal Leadframes | MACDERMID ACUMEN, INC. | 2013-02-21 | — | — | US | claimed |
| WO-2011004298-A1 | MONTELUKAST HEXAMETHYLENEDIAMINE SALT AND ITS USE FOR THE PREPARATION OF MONTELUKAST SODIUM | ALEMBIC LIMITED (IN) | 2011-01-13 | — | — | WO | claimed |
| WO-2007088545-A2 | NOVEL PROCESS FOR PREPARING 1-(MERCAPTOMETHYL) CYCLOPROPANEACETIC ACID, A USEFUL INTERMEDIATE IN THE PREPARATION OF MONTELUKAST AND SALTS THEREOF | CHEMAGIS LTD. (IL) | 2007-08-09 | — | — | WO | claimed |
| EP-1474386-A1 | PROCESS FOR THE PREPARATION OF 1-(MERCAPTOMETHYL)-CYCLOPROPANEACETIC ACID | Delmar Chemicals Inc. (CA) | 2004-11-10 | — | — | EP | claimed |
| WO-2003066582-A1 | PROCESS FOR THE PREPARATION OF 1-(MERCAPTOMETHYL)-CYCLOPROPANEACETIC ACID | DELMAR CHEMICALS INC. (CA) | 2003-08-14 | — | — | WO | claimed |
| EP-0805808-A1 | PROCESS FOR THE PREPARATION OF 1-(THIOMETHYL)-CYCLOPROPANEACETIC ACID | Merck & Co., Inc. (US) | 1997-11-12 | — | — | EP | claimed |
| EP-0737186-A1 | PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | MERCK & CO. INC. (US) | 1996-10-16 | — | — | EP | claimed |
| WO-1996022987-A1 | PROCESS FOR THE PREPARATION OF 1-(THIOMETHYL)-CYCLOPROPANEACETIC ACID | MERCK & CO., INC. (US) | 1996-08-01 | — | — | WO | claimed |
| WO-1995018107-A1 | PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | MERCK & CO., INC. (US) | 1995-07-06 | — | — | WO | claimed |
| CN-121378126-A | Preparation method of montelukast sodium | 艾美科健（中国）生物医药有限公司 | 2026-01-23 | — | — | CN | disclosed |
| US-5523477-A | REACTING 1,1-CYCLOPROPANEDIMETHANOL WITH DIALKYL SULFITE IN PRESENCE OF ACID OR BASE TO FORM CYCLIC SULFITE, REMOVING ALCOHOL REACTION BY-PRODUCT | MERCK & CO., INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995018107-A1 | PROCESS FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | MERCK & CO., INC. (US) | 1995-07-06 | — | — | WO | disclosed |