Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972171 | 0.95 | CPN1 (0.47) | CPN1CPB2 | |
| SCHEMBL989518 | 0.76 | — | — | |
| SCHEMBL2079843 | 0.74 | CPN1 (0.70) | CPN1CPB2 | |
| SCHEMBL9063708 | 0.74 | — | — | |
| SCHEMBL11147752 | 0.71 | TSHR (0.38) | CPN1CPB2 | |
| Lithium Ion SCHEMBL3888071 | 0.68 | SHBG (0.45) | — | |
| SCHEMBL5982259 | 0.68 | CPB2 (0.44) | CPN1CPB2 | |
| SCHEMBL25389365 | 0.68 | CPN1 (0.68) | CPN1CPB2 | |
| SCHEMBL6435945 | 0.64 | SHBG (0.45) | — | |
| SCHEMBL7630887 | 0.64 | SHBG (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114889-A1 | METHOD OF PREPARING MONTELUKAST AND INTERMEDIATES USED THEREIN | Hanmi Pharm. Co., Ltd. (KR) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008072872-A1 | METHOD OF PREPARING MONTELUKAST AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2008-06-19 | — | — | WO | disclosed |