SCHEMBL9895429

SCHEMBL9895429

CCCCCCCCO[Si](O)(O)OOC

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38
LPAR3 Q9UBY5 6/20 0.36
LPAR2 Q9HBW0 5/20 0.36
LPAR1 Q92633 2/20 0.36
NAAA Q02083 1/20 0.36
CES2 O00748 1/20 0.35
GBA1 P04062 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
EPHX1 P07099 1/20 0.34
TSHR P16473 3/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29010387 0.84 THRB (0.44) THRBMEN1HTTKMT2AMAPT
SCHEMBL28413946 0.84 THRB (0.44) THRBMEN1HTTKMT2AMAPT
SCHEMBL28005258 0.83 THRB (0.40) THRBMEN1HTTKMT2AMAPT
SCHEMBL7205636 0.79 CA12 (0.33) THRBMEN1HTTKMT2AMAPT
SCHEMBL22973779 0.79 CA12 (0.36) THRBMEN1HTTKMT2AMAPT
SCHEMBL31473039 0.78 THRB (0.40) THRBMEN1HTTKMT2AMAPT
SCHEMBL8837210 0.78 THRB (0.40) THRBMEN1HTTKMT2AMAPT
SCHEMBL28600061 0.78 THRB (0.40) THRBMEN1HTTKMT2AMAPT
SCHEMBL27822755 0.78 THRB (0.40) THRBMEN1HTTKMT2AMAPT
SCHEMBL766215 0.78 THRB (0.36) THRBMEN1HTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474300-B1 COMPOSITION FOR COSMETIC PREPARATION HAVING ULTRAVIOLET SHIELDING EFFECT AND SEBUM SOLIDIFYING ABILITY, AND COSMETIC PREPARATION MIYOSHI KASEI INC (JP) 2019-03-13 EP disclosed
US-9114266-B2 Composition for cosmetics having UV shielding effect and sebum solidifying ability, and cosmetic preparations Miyoshi Kasel, Inc. (JP) 2015-08-25 US disclosed
EP-2474300-A1 COMPOSITION FOR COSMETIC PREPARATION HAVING ULTRAVIOLET SHIELDING EFFECT AND SEBUM SOLIDIFYING ABILITY, AND COSMETIC PREPARATION Miyoshi Kasei, Inc. (JP) 2012-07-11 EP disclosed
US-20120148511-A1 COMPOSITION FOR COSMETICS HAVING UV SHIELDING EFFECT AND SEBUM SOLIDIFYING ABILITY, AND COSMETIC PREPARATIONS MIYOSHI KASEI, INC. (JP) 2012-06-14 US disclosed