Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9895336 | 0.95 | CYP19A1 (0.37) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| SCHEMBL7898598 | 0.95 | CYP19A1 (0.37) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| SCHEMBL9895036 | 0.80 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL7899904 | 0.80 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL181721 | 0.79 | HDAC8 (0.38) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| Trifluoroacetic Acid SCHEMBL9895594 | 0.78 | HDAC3 (0.49) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| SCHEMBL7899161 | 0.76 | HDAC3 (0.42) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| Trifluoroacetic Acid SCHEMBL9895008 | 0.73 | HDAC3 (0.39) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| SCHEMBL9896126 | 0.71 | HDAC3 (0.55) | HDAC1HDAC3HDAC6HDAC4HDAC8 | |
| SCHEMBL7899146 | 0.71 | HDAC3 (0.55) | HDAC1HDAC3HDAC6HDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155439-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2014-06-05 | — | — | US | disclosed |
| US-20130303576-A1 | ENZYME INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2013-11-14 | — | — | US | disclosed |
| US-20120149736-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303576-A1 | ENZYME INHIBITORS | HDAC1, HDAC4, HDAC3 | HDAC1 1/4885HDAC3 3/4885HDAC6 45/4885 |
| US-20140155439-A1 | ENZYME INHIBITORS | HDAC4, HDAC1, HDAC3 | HDAC1 2/4885HDAC3 3/4885HDAC6 77/4885 |
| US-20120149736-A1 | ENZYME INHIBITORS | HAT1, HDAC1, NAT1 | HDAC1 2/4885HDAC3 5/4885HDAC6 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.