Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989661 | 1.00 | CES2 (0.59) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL503450 | 0.82 | CES2 (0.66) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11459254 | 0.81 | CES2 (0.59) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| Benzene SCHEMBL10436420 | 0.81 | CES2 (0.69) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3126469 | 0.81 | CES2 (0.64) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| Benzene SCHEMBL10436419 | 0.81 | CES2 (0.69) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5341177 | 0.80 | CES2 (0.63) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL23037543 | 0.79 | CES2 (0.62) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9692669 | 0.79 | CES2 (0.61) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL3885239 | 0.78 | AKR1C3 (0.51) | MAPTALDH1A1SMN1; SMN2MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275870-A1 | Method of manufacturing cylinder-shaped flexographic plates using digital images | Flint Group Germany GmbH (DE) | 2011-01-19 | — | — | EP | disclosed |
| EP-1542692-A1 | AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Amgen Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1146083-B1 | USE OF A RESIN MATERIAL FOR ELECTRICAL INSULATING AND ELECTRIC WIRE AND CABLE USING THE SAME | JAPAN POLYOLEFINS CO LTD (JP) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003099284-A1 | AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| US-6479590-B1 | Electrical insulating resin material, electrical insulating material, and electric wire and cable using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 2002-11-12 | — | — | US | disclosed |
| EP-1213615-A2 | Photosensitive flexographic printing element having at least two infrared ablatable layers | BASF Drucksysteme GmbH (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-1146083-A1 | ELECTRICAL INSULATING RESIN MATERIAL, ELECTRICAL INSULATING MATERIAL, AND ELECTRIC WIRE AND CABLE USING THE SAME | Japan Polyolefins Co., Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5304619-A | Containing nitrile or nitro polar groups; high voltage | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0463402-A2 | Ethylene polymers or copolymers having improved insulating properties, compositions, and power cables made therefrom | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-01-02 | — | — | EP | disclosed |