Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.53 |
| ▸ | CES1 | P23141 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25174 | 0.93 | — | — | |
| SCHEMBL8119186 | 0.93 | CES2 (0.60) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL28191374 | 0.89 | — | — | |
| SCHEMBL28760889 | 0.89 | — | — | |
| Methyl Alcohol SCHEMBL8763782 | 0.89 | CES2 (0.56) | CES2CES1HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL28404295 | 0.89 | — | — | |
| SCHEMBL1772045 | 0.89 | CES2 (0.56) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL27472888 | 0.89 | CES2 (0.56) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL1820883 | 0.87 | — | — | |
| Alcohol SCHEMBL27971797 | 0.86 | KMT2A (0.62) | CES2CES1TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102757692-A | Thermosetting system white ink composition of LED flexible strip plate | LONGFEI DAI | 2012-10-31 | — | — | CN | claimed |
| CN-1821360-A | Methanol gasoline | LI XIANGSHENG (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-109713193-A | The method of amido grafted inorganic powder preparation coating high polymer diaphragm | 福建师范大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-109713192-A | The method of grafted inorganic powder preparation coating high polymer diaphragm | 福建师范大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-104051744-B | The improved manufacturability of ePTFE laminated films | 通用汽车环球科技运作有限责任公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-102757692-B | Thermosetting system white ink composition of LED flexible strip plate | DAI LONGFEI | 2014-11-12 | — | — | CN | disclosed |
| CN-104086827-A | Preparation method of electronic package mould cleaning rubber | UNIV NANTONG | 2014-10-08 | — | — | CN | disclosed |
| CN-104051744-A | MANUFACTURABILITY OF ePTFE LAMINATED MEMBRANES | GM GLOBAL TECH OPERATIONS INC | 2014-09-17 | — | — | CN | disclosed |
| CN-102373101-B | High-cleaning aged fuel | CHINA HYDROGEN ENERGY SECIENCE AND TECHNOLOGY BEIJING CO LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-101652338-B | Method, printing device, and formulations for decorating glass or ceramic items | XENNIA TECHNOLOGY LTD GB | 2013-06-12 | — | — | CN | disclosed |
| CN-102757692-A | Thermosetting system white ink composition of LED flexible strip plate | LONGFEI DAI | 2012-10-31 | — | — | CN | disclosed |
| EP-1514030-A1 | LIGHT WEIGHT FASTENER FOR USE ON INTERFERENCE FITS IN AUTOMATION | HI-SHEAR CORPORATION (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20050002754-A1 | Light weight fastener for use on interference fits in automation | SCHULTZ DENNIS (US) | 2005-01-06 | — | — | US | disclosed |
| WO-2003100273-A1 | LIGHT WEIGHT FASTENER FOR USE ON INTERFERENCE FITS IN AUTOMATION | HI-SHEAR CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030219328-A1 | Light weight fastener for use on interference fits in automation | HI-SHEAR CORPORATION | 2003-11-27 | — | — | US | disclosed |
| EP-0973838-A4 | STRONGLY ADHERENT FILM FORMING COMPOSITIONS WITH LOW COEFFICIENT OF FRICTION | HI SHEAR CORP (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0973838-A1 | STRONGLY ADHERENT FILM FORMING COMPOSITIONS WITH LOW COEFFICIENT OF FRICTION | HI-SHEAR CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046687-A1 | STRONGLY ADHERENT FILM FORMING COMPOSITIONS WITH LOW COEFFICIENT OF FRICTION | HI-SHEAR CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0353600-A2 | Aromatic diazonium salt, radiation sensitive composition containing the aromatic diazonium salt and method for formation of pattern using the radiation sensitive composition | HITACHI, LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |
| US-3992560-A | HALOGEN COMPOUNDS | CIBA-GEIGY AG (CH) | 1976-11-16 | — | — | US | disclosed |