Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL989770 | 0.99 | SLC6A9 (0.45) | SLC6A9CYP3A4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL988932 | 0.88 | SLC6A9 (0.57) | SLC6A9CYP3A4 | |
| Hydrochloric Acid SCHEMBL991012 | 0.82 | SLC6A9 (0.57) | SLC6A9CYP3A4 | |
| SCHEMBL989834 | 0.81 | SLC6A9 (0.49) | SLC6A9CYP3A4GRIN2CSCN3A | |
| Hydrochloric Acid SCHEMBL988959 | 0.80 | SLC6A9 (0.47) | SLC6A9CYP3A4 | |
| SCHEMBL4259230 | 0.79 | SLC6A9 (0.55) | SLC6A9CYP3A4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL4258688 | 0.78 | SLC6A9 (0.54) | SLC6A9CYP3A4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4259234 | 0.77 | SLC6A9 (0.56) | SLC6A9CYP3A4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL4258691 | 0.76 | SLC6A9 (0.55) | SLC6A9CYP3A4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL988257 | 0.76 | SLC6A9 (0.54) | SLC6A9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105502-A1 | TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | Abbott BmbH & Co. KG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2271625-A2 | TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | Abbott GmbH & Co. KG (DE) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105502-A1 | TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | GOLT1B, SLC10A1, SUGT1 | SLC6A9 73/4885CYP3A4 328/4885GRIN2D 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.