SCHEMBL9898360

SCHEMBL9898360

O=C1CC(=NOS(=O)(=O)c2ccccc2)CC(=NOS(=O)(=O)c2ccccc2)C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.50
MAPT P10636 9/20 0.50
NPSR1 Q6W5P4 6/20 0.50
MPI P34949 5/20 0.50
XBP1 P17861 4/20 0.50
HSP90AA1 P07900 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 4/20 0.49
KMT2A Q03164 4/20 0.48
MEN1 O00255 2/20 0.48
LMNA P02545 4/20 0.48
RAB9A P51151 4/20 0.48
S1PR2 O95136 3/20 0.48
HTT P42858 3/20 0.48
PKM P14618 2/20 0.48
OPRM1 P35372 1/20 0.48
OPRD1 P41143 1/20 0.48
KDM4E B2RXH2 6/20 0.47
TP53 P04637 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898358 1.00 ALDH1A1 (0.50) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL9898563 0.97 ALDH1A1 (0.50) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL2051857 0.93 MAPK1 (0.54) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL9898891 0.84 MEN1 (0.47) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL9898889 0.84 MEN1 (0.47) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL9898467 0.83 KMT2A (0.55) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL2046244 0.83 KMT2A (0.51) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL2046243 0.83 KMT2A (0.51) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL2048835 0.82 KMT2A (0.60) ALDH1A1MAPTNPSR1MPIXBP1
SCHEMBL9899210 0.81 MAPK1 (0.54) ALDH1A1MAPTNPSR1MPIXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed