SCHEMBL9898688

SCHEMBL9898688

CC(=O)ON=C1CCCC(=O)C1=O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.33
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
LMNA P02545 1/20 0.32
ALDH1A1 P00352 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.31
NPC1 O15118 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
PKM P14618 1/20 0.30
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898687 1.00 MAPT (0.33) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL9898950 0.85 MAPT (0.36) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL9898951 0.85 MAPT (0.36) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL9900335 0.84 MEN1 (0.32) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL9900338 0.84 MEN1 (0.32) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL2045183 0.80 MAPT (0.34) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL2045185 0.80 MAPT (0.34) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL2051363 0.79 MAPT (0.35) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL2051360 0.79 MAPT (0.35) MAPTKMT2AMEN1L3MBTL1PLA2G1B
SCHEMBL9900302 0.76 GAA (0.34) MAPTL3MBTL1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed