SCHEMBL2045185

SCHEMBL2045185

CC(=O)ON=C1CCCCC1=NOC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.32
PKM P14618 3/20 0.32
FAAH O00519 1/20 0.32
ABHD16A O95870 1/20 0.32
PLA2G7 Q13093 1/20 0.32
NCEH1 Q6PIU2 1/20 0.32
DAGLB Q8NCG7 1/20 0.32
DAGLA Q9Y4D2 1/20 0.32
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045183 1.00 MAPT (0.34) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL9898950 0.87 MAPT (0.36) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL9898951 0.87 MAPT (0.36) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL2051360 0.85 MAPT (0.35) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL2051363 0.85 MAPT (0.35) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL212464 0.81 RAB9A (0.47) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL9898688 0.80 MAPT (0.33) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL9898687 0.80 MAPT (0.33) MAPTMEN1KMT2AL3MBTL1PLA2G1B
SCHEMBL212465 0.79 MEN1 (0.50) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL214510 0.79 MEN1 (0.50) MEN1KMT2AKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed