SCHEMBL9898693

SCHEMBL9898693

CCC(=O)C(=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)C(C)=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
XDH P47989 2/20 0.31
MAOB P27338 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898691 1.00 CES2 (0.38) CES2CES1MAPTLMNARAB9A
SCHEMBL9899151 0.89 CES2 (0.41) CES2CES1MAPTLMNARAB9A
SCHEMBL9899152 0.89 CES2 (0.41) CES2CES1MAPTLMNARAB9A
SCHEMBL9899482 0.87 CES2 (0.39) CES2CES1MAPTLMNARAB9A
SCHEMBL9899484 0.87 CES2 (0.39) CES2CES1MAPTLMNARAB9A
SCHEMBL9898928 0.81 CES2 (0.38) CES2CES1MAPTLMNARAB9A
SCHEMBL9898927 0.81 CES2 (0.38) CES2CES1MAPTLMNARAB9A
SCHEMBL9899557 0.81 CES2 (0.44) CES2CES1MAPTLMNARAB9A
SCHEMBL9899556 0.81 CES2 (0.44) CES2CES1MAPTLMNARAB9A
SCHEMBL9898594 0.80 CES2 (0.41) CES2CES1MAPTLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed