SCHEMBL9898720

SCHEMBL9898720

C[Si](C)(C)ON=C1C=CC(=O)C=C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.40
ALDH1A1 P00352 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
MAOB P27338 1/20 0.36
APEX1 P27695 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
MDM2 Q00987 1/20 0.36
DHODH Q02127 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ERBB2 P04626 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899243 0.74 KDM4E (0.32) MIFALDH1A1MAOAMAOBBLM
SCHEMBL13097729 0.69 MIF (0.44) MIFALDH1A1BCHEPOLBMAOA
SCHEMBL10052269 0.69 ALDH1A1 (0.42) MIFALDH1A1BCHEPOLBMAOA
SCHEMBL5161488 0.67 MIF (0.54) MIFALDH1A1BCHEPOLBMAOA
SCHEMBL5160814 0.67 MIF (0.39) MIFALDH1A1BCHEPOLBMAOA
SCHEMBL9898335 0.65
SCHEMBL12330836 0.64
SCHEMBL15438913 0.64 MIF (0.40) MIFALDH1A1BCHEPOLBMAOA
SCHEMBL2048032 0.64 IDO1 (0.33)
SCHEMBL1255910 0.63 ALDH1A1 (0.57) MIFALDH1A1BCHEPOLBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed