Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089305 | 0.87 | TSHR (0.36) | TSHRSMN1; SMN2ALDH1A1TDP1KDM4E | |
| SCHEMBL19380536 | 0.85 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1KDM4E | |
| SCHEMBL33078 | 0.85 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1KDM4E | |
| SCHEMBL24086890 | 0.84 | KDM4E (0.39) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL8512181 | 0.82 | KDM4E (0.42) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL24183355 | 0.82 | KDM4E (0.42) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL13226809 | 0.79 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7542245 | 0.79 | KDM4E (0.40) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL13346535 | 0.76 | KDM4E (0.38) | TSHRALDH1A1TDP1KDM4EMAPK1 | |
| SCHEMBL22264018 | 0.76 | KDM4E (0.45) | TSHRALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651996-B1 | TRANSPARENT LAYER FORMING POLYMER | PROMERUS LLC (US) | 2018-06-06 | — | — | EP | disclosed |
| US-8829087-B2 | Transparent layer forming polymer | PROMERUS, LLC (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829087-B2 | Transparent layer forming polymer | PROMERUS, LLC (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829087-B2 | Transparent layer forming polymer | PROMERUS, LLC (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2651996-A1 | TRANSPARENT LAYER FORMING POLYMER | Promerus, LLC (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082705-A1 | TRANSPARENT LAYER FORMING POLYMER | PROMERUS LLC (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120149815-A1 | Transparent Layer Forming Polymer | PROMERUS LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149815-A1 | Transparent Layer Forming Polymer | PROMERUS LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149815-A1 | Transparent Layer Forming Polymer | PROMERUS LLC (US) | 2012-06-14 | — | — | US | disclosed |