SCHEMBL8512181

SCHEMBL8512181

C1=CC2CC1CC2CCOCCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24183355 1.00 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL16574231 0.91 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24086890 0.90 KDM4E (0.39) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL16569816 0.89 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL19380719 0.89 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL13346535 0.88 KDM4E (0.38) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL15105564 0.86 KDM4E (0.37) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL1012047 0.84 KDM4E (0.48) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL23619098 0.83 ALDH1A1 (0.39) KDM4EALDH1A1TDP1
SCHEMBL4787657 0.83 KDM4E (0.43) KDM4EALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109313388-B Negative photosensitive composition 住友电木株式会社 2022-06-21 CN claimed
US-10712661-B2 Negative tone photosensitive compositions PROMERUS, LLC (US) 2020-07-14 US claimed
US-20170357156-A1 NEGATIVE TONE PHOTOSENSITIVE COMPOSITIONS PROMERUS, LLC (US) 2017-12-14 US claimed
EP-4744462-A1 COMPOSITION Merck Patent GmbH (DE) 2026-05-20 EP disclosed
EP-4605438-A1 COMPOSITION Merck Patent GmbH (DE) 2025-08-27 EP disclosed
EP-3565850-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2025-07-23 EP disclosed
CN-120077076-A Composition and method for producing the same 默克专利有限公司 2025-05-30 CN disclosed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US disclosed
WO-2025012183-A1 COMPOSITION MERCK PATENT GMBH (DE) 2025-01-16 WO disclosed
CN-116096760-B Hindered amine stabilized UV-active organopalladium catalyzed polycycloolefin compositions as optical materials 住友电木株式会社 2024-08-02 CN disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 CN disclosed
WO-2017117483-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 WO disclosed
US-20170190810-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 US disclosed
US-20170190810-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 US disclosed
US-9261781-B2 Preparation of norbornane-based PAC ballasts SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-16 US disclosed
US-20130323640-A1 Preparation of Norbornane-based PAC Ballasts SUMITOMO BAKELITE CO., LTD. (JP) 2013-12-05 US disclosed
US-8530133-B2 Preparation of norbornane-based PAC ballasts PROMERUS, LLC (US) 2013-09-10 US disclosed
EP-2622410-A1 NORBORNANE-BASED PAC BALLAST AND POSITIVE-TONE PHOTOSENSITIVE RESIN COMPOSITION ENCOMPASSING THE PAC Promerus, LLC (US) 2013-08-07 EP disclosed
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts PROMERUS LLC (US) 2012-05-31 US disclosed
WO-2012044719-A1 NORBORNANE-BASED PAC BALLAST AND POSITIVE-TONE PHOTOSENSITIVE RESIN COMPOSITION ENCOMPASSING THE PAC PROMERUS LLC (US) 2012-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135352-A1 Preparation of Norbornane-based PAC Ballasts NBAS, PHB2, BDNF KDM4E 3783/4885ALDH1A1 2492/4885TSHR 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.