Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433481 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TSHRAOX1HPGDFDPS | |
| SCHEMBL1812724 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRAOX1HPGDFDPS | |
| SCHEMBL988687 | 0.80 | KDM4E (0.41) | ALDH1A1HPGDKDM1ATRIM24ALDH5A1 | |
| SCHEMBL1077197 | 0.79 | PTGDR2 (0.41) | ALDH1A1POLBEPAS1AR | |
| SCHEMBL3924578 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRERN1AOX1HPGD | |
| SCHEMBL16180046 | 0.76 | KDM1A (0.47) | ALDH1A1TSHRAOX1KDM1ATTR | |
| SCHEMBL16711689 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRERN1AOX1HPGD | |
| SCHEMBL24028315 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TSHRERN1AOX1HPGD | |
| SCHEMBL17969078 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TSHRERN1AOX1HPGD | |
| SCHEMBL2002821 | 0.72 | ERN1 (0.59) | ALDH1A1TSHRERN1AOX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |