SCHEMBL9898976

SCHEMBL9898976

O=C1CCCC(=NO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)C1=O

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
CYP2A6 P11509 1/20 0.33
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP1A2 P05177 1/20 0.31
F3 P13726 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898973 1.00 HTT (0.33) HTTSMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL9898744 0.87 GAA (0.38) HTTSMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL9898743 0.87 GAA (0.38) HTTSMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL9899379 0.86 HTT (0.33) HTTSMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL9899378 0.86 HTT (0.33) HTTSMN1; SMN2ALDH1A1MAOAMAOB
SCHEMBL2048167 0.81 HPGD (0.33) SMN1; SMN2GAARAB9AL3MBTL1
SCHEMBL2048165 0.81 HPGD (0.33) SMN1; SMN2GAARAB9AL3MBTL1
SCHEMBL9899470 0.78 CYP2A6 (0.38) CYP2A6CYP1A2
SCHEMBL9899471 0.78 CYP2A6 (0.38) CYP2A6CYP1A2
SCHEMBL9897377 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
CN-103282386-B Polymers functionalized with oxime compounds containing acyl groups BRIDGESTONE CORP 2015-07-22 CN disclosed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO disclosed