SCHEMBL9899124

SCHEMBL9899124

O=C1CC(=O)CC(=NO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9897380 0.96 CYP1A2 (0.39) CYP1A2CFTRGOPCCYP2A6
SCHEMBL9897382 0.96 CYP1A2 (0.39) CYP1A2CFTRGOPCCYP2A6
SCHEMBL9898028 0.83 MEN1 (0.38) CYP1A2GAAMAPTCYP2A6
SCHEMBL9898026 0.83 MEN1 (0.38) CYP1A2GAAMAPTCYP2A6
SCHEMBL9899497 0.82 CYP2A6 (0.34) CYP1A2GAACYP2A6
SCHEMBL9898838 0.80 GAA (0.44) CYP1A2GAAMAPT
SCHEMBL9898839 0.80 GAA (0.44) CYP1A2GAAMAPT
SCHEMBL2044914 0.79 GAA (0.33) GAA
SCHEMBL2051863 0.76 GAA (0.33) GAA
SCHEMBL2051864 0.76 GAA (0.33) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
CN-103282386-B Polymers functionalized with oxime compounds containing acyl groups BRIDGESTONE CORP 2015-07-22 CN disclosed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed