SCHEMBL9899276

SCHEMBL9899276

CC(=O)CCC(C)=NOC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.40
SLC15A2 Q16348 1/20 0.40
PKM P14618 1/20 0.32
HTT P42858 1/20 0.31
ACHE P22303 1/20 0.30
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899275 1.00 ALDH1A1 (0.48) ALDH1A1LMNASLC15A2PKMHTT
SCHEMBL2050853 0.93 ALDH1A1 (0.36) ALDH1A1LMNAPKM
SCHEMBL2050851 0.93 ALDH1A1 (0.36) ALDH1A1LMNAPKM
SCHEMBL213904 0.81 HDAC3 (0.42) ALDH1A1LMNAPKM
SCHEMBL213905 0.81 HDAC3 (0.42) ALDH1A1LMNAPKM
SCHEMBL9898282 0.78 ALDH1A1 (0.50) ALDH1A1LMNASLC15A2HTTACHE
SCHEMBL9898646 0.78 HTT (0.48) ALDH1A1LMNAPKMHTT
SCHEMBL9898280 0.78 ALDH1A1 (0.50) ALDH1A1LMNASLC15A2HTTACHE
SCHEMBL9898648 0.78 HTT (0.48) ALDH1A1LMNAPKMHTT
SCHEMBL18840170 0.77 CES1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed