Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899336 | 1.00 | KMT2A (0.44) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL2049293 | 0.91 | NPC1 (0.43) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL2049290 | 0.91 | NPC1 (0.43) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9897841 | 0.87 | KMT2A (0.46) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9897839 | 0.87 | KMT2A (0.46) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9900341 | 0.84 | SMN1; SMN2 (0.46) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9900343 | 0.84 | SMN1; SMN2 (0.46) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL2044803 | 0.82 | ATM (0.43) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL2044801 | 0.82 | ATM (0.43) | KMT2ATDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL9900465 | 0.81 | NR4A2 (0.49) | KMT2ATDP1MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |