Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 1.00 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.63 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.63 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | TDO2 | P48775 | 2/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899801 | 1.00 | TGM2 (1.00) | TGM2CDYL2CDYLCDY1; CDY1BIDO1 | |
| SCHEMBL9899719 | 0.91 | TGM2 (1.00) | TGM2CDYL2CDYLCDY1; CDY1BIDO1 | |
| SCHEMBL9899717 | 0.91 | TGM2 (1.00) | TGM2CDYL2CDYLCDY1; CDY1BIDO1 | |
| SCHEMBL9899765 | 0.86 | TGM2 (1.00) | TGM2CCNB2CDK1HSP90AA1CCNB1 | |
| SCHEMBL9901016 | 0.86 | TGM2 (1.00) | TGM2CDYL2CDYLCDY1; CDY1BCCNB2 | |
| SCHEMBL9899763 | 0.86 | TGM2 (1.00) | TGM2CCNB2CDK1HSP90AA1CCNB1 | |
| SCHEMBL9901014 | 0.86 | TGM2 (1.00) | TGM2CDYL2CDYLCDY1; CDY1BCCNB2 | |
| SCHEMBL9900052 | 0.84 | TGM2 (1.00) | TGM2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL9900055 | 0.84 | TGM2 (1.00) | TGM2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL9900914 | 0.82 | TGM2 (1.00) | TGM2CCNB2CDK1HSP90AA1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078519-A2 | 3-ACYLIDENE-2-OXOINDOLE DERIVATIVES FOR INHIBITION OF TRANSGLUTAMINASE 2 | NUMERATE, INC. (US) | 2012-06-14 | — | — | WO | disclosed |