SCHEMBL9900263

SCHEMBL9900263

CON=C(CCC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.53
ALDH1A1 P00352 2/20 0.49
GAA P10253 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 4/20 0.48
LMNA P02545 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
PPARA Q07869 2/20 0.48
KMT2A Q03164 4/20 0.47
POLB P06746 2/20 0.46
MAPK1 P28482 2/20 0.46
USP2 O75604 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CTNNB1 P35222 1/20 0.46
WNT3A P56704 1/20 0.46
MEN1 O00255 2/20 0.45
HPGD P15428 2/20 0.45
RAB9A P51151 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9900261 1.00 NR4A2 (0.53) NR4A2ALDH1A1GAACYP2C19MAPT
SCHEMBL9899584 0.90 L3MBTL1 (0.55) NR4A2GAAMAPTLMNAL3MBTL1
SCHEMBL9899585 0.90 L3MBTL1 (0.55) NR4A2GAAMAPTLMNAL3MBTL1
SCHEMBL2046346 0.89 DRD4 (0.50) ALDH1A1CYP2C19MAPTLMNAL3MBTL1
SCHEMBL2046347 0.89 DRD4 (0.50) ALDH1A1CYP2C19MAPTLMNAL3MBTL1
SCHEMBL11248774 0.88 PPARA (0.60) NR4A2GAAPPARAPPARG
SCHEMBL9897582 0.83 NR4A2 (0.50) NR4A2ALDH1A1GAACYP2C19MAPT
SCHEMBL9897583 0.83 NR4A2 (0.50) NR4A2ALDH1A1GAACYP2C19MAPT
SCHEMBL9899465 0.83 MAPT (0.54) NR4A2ALDH1A1GAACYP2C19MAPT
SCHEMBL9899464 0.83 MAPT (0.54) NR4A2ALDH1A1GAACYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO disclosed