Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.48 |
| ▸ | CES2 | O00748 | 7/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900520 | 1.00 | CES1 (0.48) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL7921554 | 0.81 | — | — | |
| SCHEMBL7921557 | 0.81 | — | — | |
| SCHEMBL9900155 | 0.80 | CES1 (0.46) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL9900156 | 0.80 | CES1 (0.46) | CES1CES2HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL9434753 | 0.77 | FFAR3 (0.33) | CES1CES2FFAR3ALDH1A1 | |
| SCHEMBL9898953 | 0.77 | CES1 (0.42) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL9898952 | 0.77 | CES1 (0.42) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL2047388 | 0.74 | TRPA1 (0.33) | — | |
| SCHEMBL10364908 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| CN-103282386-B | Polymers functionalized with oxime compounds containing acyl groups | BRIDGESTONE CORP | 2015-07-22 | — | — | CN | disclosed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |