Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167096 | 0.84 | MEN1 (0.58) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL12954646 | 0.84 | ADORA2A (0.64) | MEN1KMT2A | |
| SCHEMBL12480165 | 0.79 | HCRTR2 (0.60) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL25062733 | 0.76 | MEN1 (0.51) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL25062591 | 0.75 | MEN1 (0.49) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL12479314 | 0.74 | HCRTR2 (0.80) | HCRTR2HCRTR1 | |
| SCHEMBL9956334 | 0.74 | IMPDH2 (0.56) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL25062899 | 0.74 | MEN1 (0.51) | MEN1KMT2AHCRTR2HCRTR1 | |
| SCHEMBL16612875 | 0.73 | HCRTR2 (0.75) | HCRTR2HCRTR1 | |
| SCHEMBL13407888 | 0.73 | GSK3B (0.71) | MEN1KMT2AHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649068-A1 | OXAZOLYL-METHYLETHER DERIVATIVES AS ALX RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077049-A1 | OXAZOLYL-METHYLETHER DERIVATIVES AS ALX RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-14 | — | — | WO | disclosed |