Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900555 | 0.93 | PLA2G7 (0.47) | PLA2G7AR | |
| SCHEMBL9902064 | 0.92 | SLC22A12 (0.42) | PLA2G7AR | |
| SCHEMBL9900408 | 0.91 | PLA2G7 (0.56) | PLA2G7AR | |
| SCHEMBL9900816 | 0.90 | PLA2G7 (0.47) | PLA2G7AR | |
| SCHEMBL9900524 | 0.90 | PLA2G7 (0.43) | PLA2G7AR | |
| SCHEMBL9108483 | 0.87 | PLA2G7 (0.44) | PLA2G7AR | |
| SCHEMBL9901544 | 0.87 | DAO (0.45) | PLA2G7 | |
| SCHEMBL9901506 | 0.84 | PLA2G7 (0.57) | PLA2G7 | |
| SCHEMBL9108673 | 0.84 | PLA2G7 (0.46) | PLA2G7 | |
| SCHEMBL9901101 | 0.84 | PLA2G7 (0.53) | PLA2G7AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649053-A1 | PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES OR CONDITIONS MEDIATED BY LP - PLA2 | Glaxo Group Limited (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076435-A1 | PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES OR CONDITIONS MEDIATED BY LP - PLA2 | GLAXO GROUP LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |