SCHEMBL990074

SCHEMBL990074

O=C(O)C1=CCc2ccccc2O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
NOTUM Q6P988 3/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HCAR2 Q8TDS4 1/20 0.36
CYP2C9 P11712 1/20 0.35
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ACSL1 P33121 1/20 0.33
ALOX5 P09917 2/20 0.33
LMNA P02545 1/20 0.33
P2RX4 Q99571 1/20 0.33
DAO P14920 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30505283 1.00 MAOA (0.42) MAOAMAOBNOTUMGAAKDM4E
Hydrochloric Acid SCHEMBL6994202 0.98 MAOA (0.41) MAOAMAOBNOTUMGAAKDM4E
Acetic Acid SCHEMBL27738056 0.95 MAOA (0.38) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL29569443 0.84 MAOA (0.41) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL2971412 0.84 MAOA (0.41) MAOAMAOBNOTUMGAAKDM4E
Hydrochloric Acid SCHEMBL19744197 0.82 MAOA (0.39) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL13176581 0.81 MAOA (0.38) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL19691103 0.81 MAOA (0.38) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL9319857 0.81 MAOA (0.38) MAOAMAOBNOTUMGAAKDM4E
SCHEMBL3629324 0.80 MAOB (0.37) MAOAMAOBGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107929743-A Treat the high penetrating power prodrugs composition and medical composition of pulmonary disease 苏州泰飞尔医药有限公司 2018-04-20 CN claimed
CN-107250189-A Crosslinking polydiene propylamine copolymer for treating diabetes B 建新公司 2017-10-13 CN claimed
CN-101092415-B Compound of new benzo heterocycle categories, preparation method and application SHANGHAI INST MATERIA MEDICA 2011-04-27 CN claimed
WO-2009105723-A2 NOVEL METHODS FOR BONE TREATMENT BY MODULATING AN ARACHIDONIC ACID METABOLIC OR SIGNALING PATHWAY ACCELALOX, INC. (US) 2009-08-27 WO claimed
CN-101092415-A Compound of new benzo heterocycle categories, preparation method and application SHANGHAI INST OF MEDICINES C A (CN) 2007-12-26 CN claimed
CN-1196692-C Substituted benzopyran derivatives for the treatment of inflammation SEARLE & CO (US) 2005-04-13 CN claimed
CN-1515566-A Substituted chromene derivative for curing inflammation G.D. 2004-07-28 CN claimed
CN-1257489-A Substituted benzopyran derivatives for the treatment of inflammation SEARLE & CO (US) 2000-06-21 CN claimed
EP-0977748-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2000-02-09 EP claimed
WO-1998047890-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-10-29 WO claimed
EP-0331078-A2 Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1989-09-06 EP claimed
US-12496305-B2 Detection for determining corticosteroid responsiveness THE CLEVELAND CLINIC FOUNDATION (US) 2025-12-16 US disclosed
US-12092648-B2 Detection of glucuronidated and 3-bromotyrosine THE CLEVELAND CLINIC FOUNDATION (US) 2024-09-17 US disclosed
WO-2024107030-A1 NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME 주식회사 엘지화학 2024-05-23 WO disclosed
EP-3733658-B1 PRENYLATED BENZOPYRANES AS PPAR AGONISTS UNIV VALENCIA (ES) 2023-02-22 EP disclosed
CN-85105645-A The method for making of 1-benzopyran derivatives 1987-01-28 CN disclosed
EP-0162975-A1 P-alkyl or cycloalkyl phenoxy alkanols and alkanol esters and use for the treatment of allergic conditions PHARMACO DEVELOPMENT PARTNERS (US) 1985-12-04 EP disclosed
US-4543362-A P-Alkyl or cycloalkyl phenoxy alkanols and alkanol esters and process for the treatment of allergic conditions Berger, Frank M. (US) 1985-09-24 US disclosed
US-4451474-A T-Butyl-phenoxy-alkylene esters of benzoic and nicotinic acids, compositions containing same and their antihistaminic method of use Berger, Frank M. (US) 1984-05-29 US disclosed
US-4072710-A FROM SILYL ESTER AND THIONYL CHLORIDE PALOMO COLL A L 1978-02-07 US disclosed