Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901527 | 0.80 | PTGS2 (0.34) | PTPN1EGFRMEN1KMT2ATSHR | |
| SCHEMBL14031906 | 0.71 | TAAR1 (0.35) | PTPN1EGFR | |
| SCHEMBL20819649 | 0.70 | PTPN1 (0.35) | PTPN1EGFRMEN1KMT2ATSHR | |
| SCHEMBL15306021 | 0.70 | PTPN1 (0.41) | PTPN1EGFRMEN1KMT2ATSHR | |
| SCHEMBL17280419 | 0.70 | PTPN1 (0.41) | PTPN1EGFRMEN1KMT2ATSHR | |
| SCHEMBL18202144 | 0.69 | PTPN1 (0.43) | PTPN1EGFRMEN1KMT2A | |
| SCHEMBL20819535 | 0.69 | PTGDR2 (0.37) | EGFRMEN1KMT2ATSHR | |
| SCHEMBL20819570 | 0.68 | KMT2A (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL9900845 | 0.68 | PTPN1 (0.47) | PTPN1 | |
| SCHEMBL31690574 | 0.68 | PTPN1 (0.47) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947365-A2 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | Bionomics Limited (AU) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020000065-A2 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2020-01-02 | — | — | WO | disclosed |
| EP-3555073-A1 | HYDANTOIN MODULATORS OF KV3 CHANNELS | Autifony Therapeutics Limited (GB) | 2019-10-23 | — | — | EP | disclosed |
| EP-3390394-A1 | HYDANTOIN MODULATORS OF KV3 CHANNELS | Autifony Therapeutics Limited (GB) | 2018-10-24 | — | — | EP | disclosed |
| WO-2018109484-A1 | HYDANTOIN MODULATORS OF KV3 CHANNELS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017103604-A1 | HYDANTOIN MODULATORS OF KV3 CHANNELS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-22 | — | — | WO | disclosed |
| EP-2788339-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | Autifony Therapeutics Limited (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2649066-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | Autifony Therapeutics Limited (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2013083994-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2013-06-13 | — | — | WO | disclosed |
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |