Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC2 | O75106 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13518531 | 0.97 | TAAR1 (0.54) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL9860834 | 0.85 | GFER (0.42) | TAAR1MAOBL3MBTL1MAOA | |
| SCHEMBL1722292 | 0.84 | TAAR1 (0.52) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL6224187 | 0.82 | TAAR1 (0.50) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL7437052 | 0.82 | TAAR1 (0.68) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL2990337 | 0.81 | TAAR1 (0.54) | TAAR1MAOBIDO1LOXL2AOC3 | |
| 1,2-Dichloroethane SCHEMBL16781679 | 0.78 | IDO1 (0.45) | TAAR1IDO1LOXL2AGXT | |
| SCHEMBL10574057 | 0.77 | TAAR1 (0.62) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL2320532 | 0.77 | TAAR1 (0.62) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL9552844 | 0.77 | MAOB (0.46) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113510-A1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | claimed |
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |
| CN-114716296-B | Efficient halogenation synthesis method of alkyl halide | 润药仁智(北京)科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117164480-A | Method for preparing cyanamide and mercaptan | 华南理工大学 | 2023-12-05 | — | — | CN | disclosed |
| EP-4257593-A1 | CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION | SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) | 2023-10-11 | — | — | EP | disclosed |
| CN-114716296-A | Efficient halogenation synthesis method of alkyl halide | 北京大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20220025424-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE AMINOCYCLOPROPANES | IMAGO BIOSCIENCES, INC. | 2022-01-27 | — | — | US | disclosed |
| CN-109476658-B | Substituted 5,6,7, 8-tetrahydro [1,2,4] triazolo [4,3-a ] pyridin-3 (2H) -ones and 2,5,6, 7-tetrahydro-3H-pyrrolo [2,1-c ] [1,2,4] triazol-3-ones and uses thereof | 拜耳公司 | 2021-08-10 | — | — | CN | disclosed |
| EP-2897599-B1 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | UNIV TEMPLE (US) | 2020-12-30 | — | — | EP | disclosed |
| WO-1989010369-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0289881-A2 | 2-Aminoalkyl-4-benzyl-1-(2H)-phthalazinone derivatives | ASTA Medica Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | disclosed |
| US-4681879-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4608374-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4350822-A | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |
| US-4185115-A | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113510-A1 | QUINUCLIDINOL DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM2, CHRM1, CHRM3 | TAAR1 96/4885MAOB 152/4885IDO1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.