SCHEMBL2320532

SCHEMBL2320532

Fc1ccc(CCCc2ccc(F)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.62
IDO1 P14902 2/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
MAOB P27338 1/20 0.52
AOC3 Q16853 1/20 0.50
CYP19A1 P11511 1/20 0.48
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
AGXT P21549 1/20 0.46
CHRM2 P08172 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10574057 0.94 TAAR1 (0.62) TAAR1IDO1LOXL2MAOBAOC3
SCHEMBL19651375 0.92 MAOB (0.64) TAAR1IDO1LOXL2MAOBAOC3
SCHEMBL10571903 0.91 TAAR1 (0.59) TAAR1IDO1LOXL2MAOBAOC3
SCHEMBL6981704 0.89 HTR2A (0.60) TAAR1MAOB
SCHEMBL2303570 0.87 DRD2 (0.54) TAAR1
SCHEMBL21422626 0.87 L3MBTL1 (0.60) TAAR1IDO1MAOBAOC3PTGS1
SCHEMBL7437052 0.87 TAAR1 (0.68) TAAR1IDO1LOXL2MAOBAOC3
SCHEMBL7210161 0.84 TAAR1 (0.52) TAAR1IDO1LOXL2MAOBAOC3
SCHEMBL22621170 0.84 MAOB (0.61) TAAR1IDO1LOXL2MAOB
SCHEMBL386493 0.84 TAAR1 (0.52) TAAR1IDO1LOXL2MAOBAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344091-B2 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same SAMSUNG SDI CO. LTD. (KR) 2013-01-01 US disclosed
EP-2349484-A2 HETEROARYL DERIVATIVES AS DGAT1 INHIBITORS Novartis AG (CH) 2011-08-03 EP disclosed
WO-2010007046-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-01-21 WO disclosed
US-20090280384-A1 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same SAMSUNG SDI CO., LTD., A CORPORATION CHARTERED IN AND EXISTING UNDET THE LAWS OF THE REPUBLIC OF KOREA (KR) 2009-11-12 US disclosed