Bromide

Bromide

SCHEMBL9901166

Br.N#Cc1cccnc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28776 0.98
SCHEMBL2014183 0.98 CYP11B2 (0.61)
SCHEMBL29434996 0.98
Water SCHEMBL28116587 0.98
Water SCHEMBL4803706 0.98 CYP11B2 (0.61)
Benzene SCHEMBL15416232 0.95 CYP11B2 (0.59)
Hydrochloric Acid SCHEMBL22031517 0.95 CYP11B2 (0.59)
Hydrochloric Acid SCHEMBL29882448 0.95 CYP11B2 (0.59)
Hydrochloric Acid SCHEMBL6439131 0.95
Hydrochloric Acid SCHEMBL32685327 0.95 CYP11B2 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2465849-A1 3-cyanopyridinium tricyanomethanides as ionic liquids Lonza Ltd. (CH) 2012-06-20 EP claimed
WO-2012076367-A1 3-CYANOPYRIDINIUM TRICYANOMETHANIDES LONZA LTD (CH) 2012-06-14 WO claimed
EP-2465849-A1 3-cyanopyridinium tricyanomethanides as ionic liquids Lonza Ltd. (CH) 2012-06-20 EP disclosed
WO-2012076367-A1 3-CYANOPYRIDINIUM TRICYANOMETHANIDES LONZA LTD (CH) 2012-06-14 WO disclosed