Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902659 | 0.93 | MAPKAPK2 (0.38) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9901327 | 0.93 | MAOB (0.37) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9902453 | 0.91 | MAOB (0.36) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9111055 | 0.86 | MAPKAPK2 (0.42) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9901444 | 0.85 | MAOB (0.35) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9902078 | 0.84 | MAPKAPK2 (0.38) | MAOBMAOAACHEMAPTMAPKAPK2 | |
| SCHEMBL9113402 | 0.82 | MAPKAPK2 (0.51) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9112027 | 0.82 | MAPK14 (0.46) | MAOBPKMMAOASMN1; SMN2MAPT | |
| SCHEMBL9902538 | 0.81 | MAOB (0.36) | MAOBPKMMAOAMTNR1AMTNR1B | |
| SCHEMBL9109270 | 0.80 | MAPKAPK2 (0.44) | MAOBPKMMAOAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | disclosed |