Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901363 | 1.00 | FDPS (0.60) | FDPSHDAC1HDAC2HDAC8APP | |
| SCHEMBL9901361 | 1.00 | FDPS (0.60) | FDPSHDAC1HDAC2HDAC8APP | |
| SCHEMBL9947558 | 0.91 | HDAC1 (0.72) | FDPSHDAC1HDAC2HDAC8KDM4E | |
| SCHEMBL19695927 | 0.90 | FDPS (0.73) | FDPSAPPKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30289943 | 0.88 | KDM4E (0.69) | FDPSHDAC1HDAC2HDAC8KDM4E | |
| SCHEMBL21715528 | 0.88 | KDM4E (0.69) | FDPSHDAC1HDAC2HDAC8KDM4E | |
| SCHEMBL20455920 | 0.88 | KDM4E (0.69) | FDPSHDAC1HDAC2HDAC8KDM4E | |
| SCHEMBL9947551 | 0.87 | HDAC1 (0.61) | FDPSHDAC1HDAC2HDAC8APP | |
| SCHEMBL31682437 | 0.85 | HDAC1 (0.65) | HDAC1HDAC2HDAC8APPKDM4E | |
| SCHEMBL15020459 | 0.85 | HDAC1 (0.65) | HDAC1HDAC2HDAC8APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076696-A1 | NEW METAL CARBONYL COMPLEXES OF CURCUMIN DERIVATIVES, THEIR SYNTHESIS AND THEIR USES IN THERAPEUTIC APPLICATION | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2012-06-14 | — | — | WO | disclosed |