Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243595 | 0.80 | CYP3A4 (0.44) | MGLLKCNA5 | |
| SCHEMBL1243596 | 0.80 | KCNA5 (0.41) | MGLLKCNA5 | |
| SCHEMBL1243080 | 0.79 | CYP3A4 (0.41) | MGLLKCNA5 | |
| SCHEMBL1243062 | 0.79 | KCNA5 (0.42) | MGLLKCNA5 | |
| SCHEMBL1242438 | 0.78 | MGLL (0.46) | MGLLKCNA5 | |
| SCHEMBL1240757 | 0.78 | KCNA5 (0.42) | MGLLKCNA5 | |
| SCHEMBL1242330 | 0.77 | MGLL (0.46) | MGLLKCNA5 | |
| SCHEMBL1242190 | 0.77 | KCNA5 (0.41) | MGLLKCNA5 | |
| SCHEMBL1243188 | 0.76 | MGLL (0.42) | MGLLKCNA5 | |
| SCHEMBL1242037 | 0.75 | KCNA5 (0.45) | MGLLKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781635-B1 | POTASSIUM CHANNEL INHIBITORS | MERCK SHARP & DOHME (US) | 2012-06-13 | — | — | EP | claimed |