Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16994523 | 1.00 | P2RX7 (0.43) | P2RX7KMT2AKDM4EGAAMEN1 | |
| SCHEMBL9902380 | 0.92 | P2RX7 (0.37) | P2RX7KMT2AKDM4EGAAMEN1 | |
| SCHEMBL16994497 | 0.92 | P2RX7 (0.37) | P2RX7KMT2AKDM4EGAAMEN1 | |
| SCHEMBL9902381 | 0.92 | P2RX7 (0.37) | P2RX7KMT2AKDM4EGAAMEN1 | |
| SCHEMBL16994518 | 0.88 | KDM4E (0.51) | P2RX7KMT2AKDM4EGAAABCC9 | |
| SCHEMBL9902154 | 0.88 | KDM4E (0.38) | P2RX7KMT2AKDM4EGAAMEN1 | |
| SCHEMBL9902190 | 0.88 | P2RX7 (0.41) | P2RX7KMT2AKDM4EGAARECQL | |
| SCHEMBL9902217 | 0.88 | KDM4E (0.38) | P2RX7KMT2AKDM4EGAATHRB | |
| SCHEMBL9902214 | 0.88 | KDM4E (0.38) | P2RX7KMT2AKDM4EGAATHRB | |
| SCHEMBL16994515 | 0.88 | P2RX7 (0.41) | P2RX7KMT2AKDM4EGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |