Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903235 | 0.88 | GRM5 (0.31) | GRM5ALDH1A1 | |
| SCHEMBL16994520 | 0.87 | KDM4E (0.37) | GAAKDM4EKMT2AGRM5 | |
| SCHEMBL9903064 | 0.87 | KDM4E (0.37) | GAAKDM4EKMT2AGRM5 | |
| SCHEMBL16994492 | 0.83 | KDM4E (0.51) | GAAKDM4EKMT2AALDH1A1 | |
| SCHEMBL9902621 | 0.81 | KDM4E (0.32) | GAAKDM4EKMT2A | |
| SCHEMBL16994486 | 0.81 | KDM4E (0.32) | GAAKDM4EKMT2AGRM5 | |
| SCHEMBL9902618 | 0.81 | KDM4E (0.32) | GAAKDM4EKMT2A | |
| SCHEMBL9901565 | 0.80 | KMT2A (0.38) | GAAKDM4EKMT2A | |
| SCHEMBL9901564 | 0.80 | KMT2A (0.38) | GAAKDM4EKMT2A | |
| SCHEMBL9901299 | 0.79 | GAA (0.41) | GAAKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |