Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17271397 | 0.93 | GAA (0.36) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17271396 | 0.93 | GAA (0.36) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16994507 | 0.86 | P2RX7 (0.43) | GAAKDM4EKMT2AALDH1A1NPC1 | |
| SCHEMBL9902441 | 0.86 | P2RX7 (0.43) | GAAKDM4EKMT2AALDH1A1NPC1 | |
| SCHEMBL9902913 | 0.86 | KDM4E (0.39) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16994523 | 0.83 | P2RX7 (0.43) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9901441 | 0.83 | P2RX7 (0.43) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9902214 | 0.81 | KDM4E (0.38) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9902217 | 0.81 | KDM4E (0.38) | GAAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16994494 | 0.81 | KDM4E (0.43) | GAAKDM4EKMT2AP2RX7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |