Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.34 |
| ▸ | FPR3 | P25089 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16994496 | 0.89 | P2RX7 (0.39) | RAB9ASMN1; SMN2 | |
| SCHEMBL16994512 | 0.88 | P2RX7 (0.39) | KDM4ESMN1; SMN2 | |
| SCHEMBL17271378 | 0.88 | P2RX7 (0.39) | KDM4ESMN1; SMN2 | |
| SCHEMBL9905805 | 0.86 | P2RX7 (0.39) | KDM4E | |
| SCHEMBL9905806 | 0.86 | P2RX7 (0.39) | KDM4E | |
| SCHEMBL16994500 | 0.86 | P2RX7 (0.39) | KDM4E | |
| SCHEMBL9902154 | 0.86 | KDM4E (0.38) | FPR2FPR3OPRM1OPRD1TDP1 | |
| SCHEMBL9901652 | 0.84 | QPCT (0.37) | QPCTRAB9ASMN1; SMN2 | |
| SCHEMBL16994506 | 0.84 | QPCT (0.37) | QPCTRAB9ASMN1; SMN2 | |
| SCHEMBL9901650 | 0.84 | QPCT (0.37) | QPCTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |