Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904944 | 0.83 | MMP13 (0.39) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9904932 | 0.83 | MMP13 (0.39) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9904934 | 0.83 | MMP13 (0.36) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9901158 | 0.82 | CYP2C9 (0.44) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL52487 | 0.80 | KCNH2 (0.48) | KCNH2CYP2C9KCNE1CCR1KCNQ1 | |
| SCHEMBL9901256 | 0.80 | CYP2C9 (0.42) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9904978 | 0.80 | MMP13 (0.36) | MMP13KCNH2CYP2C9SCDWDR5 | |
| SCHEMBL9901113 | 0.80 | KCNH2 (0.38) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9905205 | 0.79 | MMP13 (0.39) | MMP13KCNH2CYP2C9MMP10MMP8 | |
| SCHEMBL9901114 | 0.79 | KCNH2 (0.37) | MMP13KCNH2CYP2C9MMP10MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649077-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078834-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | claimed |
| EP-2649077-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078834-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |