SCHEMBL99019

SCHEMBL99019

COc1cc(N)c(Cl)cc1C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.73
NPC1 O15118 1/20 0.58
HTR4 Q13639 7/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2D6 P10635 2/20 0.55
HTR3A P46098 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2C9 P11712 1/20 0.55
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ALDH1A1 P00352 2/20 0.54
HTR3E A5X5Y0 1/20 0.53
SLC22A1 O15245 1/20 0.53
HTR3B O95264 1/20 0.53
LMNA P02545 1/20 0.53
MPO P05164 1/20 0.53
ADRA2A P08913 1/20 0.53
DRD2 P14416 1/20 0.53
ADRA2C P18825 1/20 0.53
DRD4 P21917 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7442414 0.98 GAA (0.71) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL7412182 0.86 GAA (0.55) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL856225 0.86 GAA (0.58) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL725809 0.86 GAA (0.73) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL7351910 0.86 GAA (0.73) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL7280230 0.86 GAA (0.73) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL29918211 0.86 GAA (0.58) GAANPC1HTR4CYP1A2CYP2D6
SCHEMBL1965781 0.85 ALDH1A1 (0.61) GAACYP3A4ALDH1A1LMNAGLA
SCHEMBL31634578 0.85 ALDH1A1 (0.61) GAACYP3A4ALDH1A1LMNAGLA
SCHEMBL3387534 0.85 ALDH1A1 (0.56) GAANPC1ALDH1A1KCNH2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1069 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977828-A Methoxychlor-pup Process for the preparation of amines 河南优凯制药有限公司 2025-05-13 CN claimed
CN-119977827-A Methoxychlor-pram intermediate and preparation method and application thereof 河南优凯制药有限公司 2025-05-13 CN claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
EP-1919909-B1 SYNTHETIC METHODS AND INTERMEDIATES FOR STEREOISOMERIC COMPOUNDS USEFUL FOR THE TREATMENT OF GASTROINTESTINAL AND CENTRAL NERVOUS SYSTEM DISORDERS ARMETHEON INC (US) 2013-08-21 EP claimed
EP-1668082-B1 LAKED AZO RED PIGMENT AND PROCESSES FOR PREPARATION AND USE BASF CATALYSTS LLC (US) 2013-01-09 EP claimed
CN-102863374-A Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders ARYX THERAPEUTICS 2013-01-09 CN claimed
CN-101258151-B Process for the synthesis of stereoisomeric compounds useful in the treatment of gastrointestinal and central nervous system disorders and intermediates ARYX THERAPEUTICS INC 2012-10-10 CN claimed
CN-101040028-B Photocrosslinkable materials ROLIC AG 2012-03-28 CN claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
EP-1503764-B1 5-HT4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF HEART FAILURE SERODUS AS (NO) 2010-01-06 EP claimed
WO-1998016511-A1 SYNTHESIS OF CISAPRIDE JANSSEN PHARMACEUTICA N.V. (BE) 1998-04-23 WO claimed
US-5717098-A GAMMA-LACTONE CHEMICAL INTERMEDIATE, USED TO PRODUCE A SINGLE ENANTIOMER OF AMINOAZANORADAMANTANE WHICH IS COUPLED TO AROMATIC ACID DERIVEATIVE TO PRODUCE A COMPOUND USEFUL AS 5-HT-AGONISTS OR ANTAGONSITS G. D. SEARLE & CO. (US) 1998-02-10 US claimed
WO-1996000729-A2 PROCESS FOR THE PREPARATION OF AZANORADAMANTANE BENZAMIDES G.D. SEARLE & CO. (US) 1996-01-11 WO claimed
WO-1995025100-A1 USE OF 4-AMINO-5-CHLORO-2-METHOXYBENZOIC ESTERS AS 5-HT4 AGONISTS SANOFI (FR) 1995-09-21 WO claimed
WO-1995021168-A1 MESO-AZANORADAMANTANES G.D. SEARLE & CO. (US) 1995-08-10 WO claimed
EP-0190915-B1 Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2]octan-3-yl) aminobenzamides SYNTHELABO (FR) 1992-10-28 EP claimed
US-4950766-A Preparation of benzamides useful as antiemetic agents ERBAMONT, INC. (US) 1990-08-21 US claimed
US-4870181-A AMIDATION OF 3-AMINOQUINUCLIDINE SALT A. H. ROBINS COMPANY, INCORPORATED (US) 1989-09-26 US claimed
EP-0314483-A1 Preparation of benzamides ERBAMONT, INC. (US) 1989-05-03 EP claimed
EP-0190915-A2 Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2]octan-3-yl) aminobenzamides SYNTHELABO (FR) 1986-08-13 EP claimed