Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898288 | 0.93 | KMT2A (0.44) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898290 | 0.93 | KMT2A (0.44) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898656 | 0.92 | KMT2A (0.47) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898655 | 0.92 | KMT2A (0.47) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898969 | 0.85 | KMT2A (0.50) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898968 | 0.85 | KMT2A (0.50) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898771 | 0.81 | KMT2A (0.46) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL9898769 | 0.81 | KMT2A (0.46) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL2045904 | 0.81 | ATM (0.40) | KMT2AMEN1HPGDKDM4EMAPT | |
| SCHEMBL2045908 | 0.81 | ATM (0.40) | KMT2AMEN1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649102-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | Bridgestone Corporation (JP) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078962-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | WO | claimed |
| EP-2649102-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | Bridgestone Corporation (JP) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078962-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | WO | disclosed |