Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903262 | 0.86 | GRIN2D (0.44) | SIGMAR1KDM4EGAAKMT2ACA1 | |
| SCHEMBL9902512 | 0.85 | SIGMAR1 (0.42) | SIGMAR1IDO1TDO2EGFRGRIN2D | |
| SCHEMBL9902476 | 0.73 | KDM4E (0.40) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902365 | 0.72 | KMT2A (0.39) | KDM4EGAAKMT2AIDO1EGFR | |
| SCHEMBL9903487 | 0.72 | KMT2A (0.45) | SIGMAR1KDM4EGAAKMT2AIDO1 | |
| SCHEMBL9901901 | 0.72 | SIGMAR1 (0.36) | SIGMAR1KDM4EIDO1GRIN2DGRIN3B | |
| SCHEMBL9902748 | 0.71 | GRIN2D (0.42) | SIGMAR1GAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL18727707 | 0.70 | EGFR (0.36) | KDM4EGAAKMT2AIDO1EGFR | |
| SCHEMBL18727708 | 0.70 | EGFR (0.36) | KDM4EGAAKMT2AIDO1EGFR | |
| SCHEMBL9902255 | 0.70 | KDM4E (0.50) | KDM4EGAAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |