Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9905571 | 0.86 | CYP1A2 (0.44) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL22995212 | 0.86 | KMT2A (0.55) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL22995437 | 0.83 | HTT (0.56) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL9902726 | 0.81 | CYP1A2 (0.36) | SMN1; SMN2KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL22995517 | 0.78 | KMT2A (0.49) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL11395624 | 0.78 | KMT2A (0.49) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL22995234 | 0.78 | KMT2A (0.47) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL8975749 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2HTTPOLBALDH1A1KDM4E | |
| SCHEMBL22995220 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1GAAHTT | |
| SCHEMBL8873130 | 0.76 | ALDH1A1 (0.41) | SMN1; SMN2HTTPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463277-B1 | METHOD FOR PRODUCING 4,6-DIALKOXY-2-CYANOMETHYLPYRIMIDINE AND SYNTHETIC INTERMEDIATE THEREOF | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2017-11-08 | — | — | EP | disclosed |
| US-8748605-B2 | Method for producing 4,6-dialkoxy-2-cyanomethylpyrimidine and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120190851-A1 | METHOD FOR PRODUCING 4,6-DIALKOXY-2-CYANOMETHYLPYRIMIDINE AND SYNTHETIC INTERMEDIATE THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2463277-A1 | METHOD FOR PRODUCING 4,6-DIALKOXY-2-CYANOMETHYLPYRIMIDINE AND SYNTHETIC INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190851-A1 | METHOD FOR PRODUCING 4,6-DIALKOXY-2-CYANOMETHYLPYRIMIDINE AND SYNTHETIC INTERMEDIATE THEREOF | DPYD, TYMP, DTYMK | SMN1; SMN2 2788/4885KMT2A 2114/4885MEN1 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.