Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242156 | 0.84 | CFTR (0.42) | CYP19A1KCNA5CREBBPCYP11B1CYP11B2 | |
| SCHEMBL1242972 | 0.78 | KCNA5 (0.46) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1242330 | 0.77 | MGLL (0.46) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1242145 | 0.77 | CYP19A1 (0.45) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1242623 | 0.76 | KCNA5 (0.44) | CYP19A1KCNA5CYP11B1CYP11B2GAA | |
| SCHEMBL1243093 | 0.76 | MGLL (0.42) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1242929 | 0.76 | KCNA5 (0.40) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1378201 | 0.75 | CYP19A1 (0.51) | CYP19A1MGLLVNN1KCNA5KCNH2 | |
| SCHEMBL1243310 | 0.75 | KCNA5 (0.40) | KCNA5KCNH2ALDH1A1 | |
| SCHEMBL1241967 | 0.75 | KCNA5 (0.40) | KCNA5KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781635-B1 | POTASSIUM CHANNEL INHIBITORS | MERCK SHARP & DOHME (US) | 2012-06-13 | — | — | EP | claimed |