Acetonitrile

Acetonitrile

SCHEMBL9903188

CC#N.O=C(O)c1cnc2ccccc2c1

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.81
CFTR P13569 1/20 0.52
TOP2A P11388 2/20 0.49
TOP2B Q02880 2/20 0.49
BCAT1 P54687 1/20 0.49
KDR P35968 1/20 0.49
MAP4K4 O95819 1/20 0.47
CSNK1G2 P78368 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47
MKNK2 Q9HBH9 1/20 0.47
MAP4K5 Q9Y4K4 1/20 0.47
RAB9A P51151 3/20 0.47
PSMD14 O00487 1/20 0.47
CYP1A2 P05177 2/20 0.46
HPGDS O60760 1/20 0.45
KDM4E B2RXH2 3/20 0.45
NPC1 O15118 2/20 0.45
MITF O75030 1/20 0.45
XBP1 P17861 1/20 0.45
PAX8 Q06710 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28182355 0.92 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
SCHEMBL29362407 0.90 MGAM (1.00) MGAMCFTRTOP2ATOP2BBCAT1
SCHEMBL28048 0.90 MGAM (1.00) MGAMCFTRTOP2ATOP2BBCAT1
Hydrochloric Acid SCHEMBL9114407 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
Fluoride SCHEMBL27513846 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
Fluoride SCHEMBL27790822 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
Hydrochloric Acid SCHEMBL1649216 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
Ammonia Solution, Strong SCHEMBL27447121 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
SCHEMBL27611260 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1
SCHEMBL27565246 0.89 MGAM (0.96) MGAMCFTRTOP2ATOP2BBCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1626051-B1 CRYSTALS OF QUINOLINECARBOXYLIC ACID DERIVATIVE SOLVATE NIPPON SHINYAKU CO LTD (JP) 2012-06-13 EP claimed
CN-100351258-C Crystals of quinolinecarboxylic acid derivative solvate. NIPPON SHINYAKU CO LTD (JP) 2007-11-28 CN claimed
CN-1780842-A crystals of quinolinecarboxylic acid derivative solvate NIPPON SHINYAKU CO LTD (JP) 2006-05-31 CN claimed
CN-104865307-A Analysis method for alcohol compound in biological sample UNIV SHANGHAI JIAOTONG 2015-08-26 CN disclosed
CN-100351258-C Crystals of quinolinecarboxylic acid derivative solvate. NIPPON SHINYAKU CO LTD (JP) 2007-11-28 CN disclosed
CN-1780842-A crystals of quinolinecarboxylic acid derivative solvate NIPPON SHINYAKU CO LTD (JP) 2006-05-31 CN disclosed