Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347528 | 0.81 | APOBEC3A (0.42) | APOBEC3AAPOBEC3G | |
| SCHEMBL3345963 | 0.79 | APOBEC3A (0.41) | APOBEC3AAPOBEC3G | |
| Toluene SCHEMBL9903136 | 0.78 | APOBEC3A (0.43) | APOBEC3AAPOBEC3G | |
| SCHEMBL3346983 | 0.78 | APOBEC3A (0.40) | APOBEC3AAPOBEC3G | |
| SCHEMBL3346719 | 0.78 | APOBEC3A (0.35) | APOBEC3AAPOBEC3G | |
| Cyclohexene SCHEMBL9903303 | 0.75 | MAP4K4 (0.36) | — | |
| SCHEMBL3346197 | 0.74 | APOBEC3A (0.37) | APOBEC3AAPOBEC3G | |
| SCHEMBL3142328 | 0.73 | APOBEC3A (0.53) | APOBEC3AAPOBEC3G | |
| SCHEMBL14629345 | 0.73 | APOBEC3A (0.49) | APOBEC3AAPOBEC3G | |
| SCHEMBL3347047 | 0.71 | APOBEC3A (0.34) | APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178742-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-07-12 | — | — | US | claimed |
| EP-2462142-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-06-13 | — | — | EP | claimed |
| US-20120178742-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-07-12 | — | — | US | disclosed |
| EP-2462142-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178742-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | GRM5, GRIK5, GRM1 | APOBEC3A 4593/4885APOBEC3G 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.