SCHEMBL990395

SCHEMBL990395

COC(C)(OC)C(Br)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22115653 0.69 ALDH1A1 (0.35)
SCHEMBL3248772 0.67
SCHEMBL4474893 0.64
SCHEMBL5274450 0.64 ALDH1A1 (0.38)
SCHEMBL8570871 0.64
SCHEMBL1778620 0.64
SCHEMBL2040354 0.62
SCHEMBL7227524 0.62
SCHEMBL7928068 0.62
SCHEMBL22401338 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111320535-B Preparation method of 3- (benzyloxy) -1-cyclobutanone 苏州楚凯药业有限公司 2022-04-01 CN claimed
CN-111320535-A Preparation method of 3- (benzyloxy) -1-cyclobutanone 苏州楚凯药业有限公司 2020-06-23 CN claimed
CN-104262121-A Method for synthesizing 1,3-dibromo-2,2-dimethoxy propane SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD 2015-01-07 CN claimed
EP-4323358-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER Hotspot Therapeutics, Inc. (US) 2024-02-21 EP disclosed
EP-4288429-A1 LACTAMS AS CBL-B INHIBITORS Genentech, Inc. (US) 2023-12-13 EP disclosed
WO-2023081853-A1 LACTAMS AS CBL-B INHIBITORS SELECTIVE OVER C-CBL GENENTECH, INC. (US) 2023-05-11 WO disclosed
US-RE49481-E1 Compounds for the treatment and prophylaxis of respiratory syncytial virus disease HOFFMANN-LA ROCHE INC. (US) 2023-04-04 US disclosed
WO-2022221704-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER HOTSPOT THERAPEUTICS, INC. (US) 2022-10-20 WO disclosed
CN-111320535-B Preparation method of 3- (benzyloxy) -1-cyclobutanone 苏州楚凯药业有限公司 2022-04-01 CN disclosed
CN-111320535-B Preparation method of 3- (benzyloxy) -1-cyclobutanone 苏州楚凯药业有限公司 2022-04-01 CN disclosed
CN-111320535-A Preparation method of 3- (benzyloxy) -1-cyclobutanone 苏州楚凯药业有限公司 2020-06-23 CN disclosed
CN-104262121-A Method for synthesizing 1,3-dibromo-2,2-dimethoxy propane SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD 2015-01-07 CN disclosed
US-8871756-B2 Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease HOFFMANN-LA ROCHE INC. (US) 2014-10-28 US disclosed
EP-2742039-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE F. Hoffmann-La Roche AG (CH) 2014-06-18 EP disclosed
US-20130196974-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE HOFFMANN-LA ROCHE INC. 2013-08-01 US disclosed
WO-2013020993-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2013-02-14 WO disclosed
EP-2271625-A2 TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY Abbott GmbH & Co. KG (DE) 2011-01-12 EP disclosed
WO-2009121872-A2 TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBOTT GMBH & CO. KG (DE) 2009-10-08 WO disclosed
EP-1807078-A1 DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS Vitae Pharmaceuticals, Inc. (US) 2007-07-18 EP disclosed
WO-2006042150-A1 DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2006-04-20 WO disclosed