Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108326 | 0.90 | PDE10A (0.46) | PDE10A | |
| SCHEMBL9104631 | 0.88 | PDE10A (0.55) | PDE10A | |
| SCHEMBL9926279 | 0.86 | PDE10A (0.67) | PDE10A | |
| SCHEMBL9108566 | 0.85 | PDE10A (0.52) | PDE10A | |
| SCHEMBL9926280 | 0.84 | PDE10A (0.63) | PDE10A | |
| SCHEMBL9904042 | 0.83 | PDE10A (0.56) | PDE10A | |
| SCHEMBL9277270 | 0.83 | PDE10A (0.55) | PDE10A | |
| SCHEMBL9926270 | 0.82 | PDE10A (0.65) | PDE10A | |
| SCHEMBL9904177 | 0.80 | PDE10A (0.57) | PDE10A | |
| SCHEMBL16145703 | 0.80 | PDE10A (0.72) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649070-B1 | TRIAZOLOPYRIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-09-17 | — | — | EP | claimed |
| EP-2649070-B1 | TRIAZOLOPYRIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-09-17 | — | — | EP | disclosed |
| EP-2649070-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076430-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-14 | — | — | WO | disclosed |