Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904042 | 0.92 | PDE10A (0.56) | PDE10AAAK1 | |
| SCHEMBL9108157 | 0.86 | PDE10A (0.62) | PDE10A | |
| SCHEMBL9118417 | 0.84 | PDE10A (0.58) | PDE10A | |
| SCHEMBL9904287 | 0.84 | PDE10A (0.79) | PDE10A | |
| SCHEMBL9108410 | 0.83 | PDE10A (0.67) | PDE10A | |
| SCHEMBL9105505 | 0.83 | PDE10A (0.78) | PDE10A | |
| SCHEMBL9108872 | 0.83 | PDE10A (0.78) | PDE10A | |
| SCHEMBL9904272 | 0.83 | PDE10A (0.45) | PDE10A | |
| SCHEMBL9107790 | 0.83 | PDE10A (0.65) | PDE10A | |
| SCHEMBL9107261 | 0.81 | PDE10A (0.80) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649070-B1 | TRIAZOLOPYRIDINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-09-17 | — | — | EP | disclosed |
| EP-2649070-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076430-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-14 | — | — | WO | disclosed |