Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990487 | 1.00 | ALDH1A1 (0.33) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL989874 | 0.88 | BACE1 (0.34) | BACE1BACE2 | |
| SCHEMBL8516042 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL8516035 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL990603 | 0.83 | BACE2 (0.39) | BACE1BACE2 | |
| SCHEMBL990539 | 0.82 | BACE1 (0.37) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL990540 | 0.82 | BACE1 (0.37) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL6919820 | 0.81 | ALDH1A1 (0.36) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL15327033 | 0.77 | BACE1 (0.43) | ALDH1A1GAATHRBHTTL3MBTL1 | |
| SCHEMBL15327032 | 0.77 | BACE1 (0.43) | ALDH1A1GAATHRBHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009897-A1 | FUSED AMINODIHYDROPYRIMIDONE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD (JP) | 2011-01-27 | — | — | WO | disclosed |