Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GZMB | P10144 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16053534 | 0.89 | GZMB (0.61) | GZMB | |
| SCHEMBL9904574 | 0.89 | GZMB (0.60) | GZMB | |
| SCHEMBL15485117 | 0.88 | GZMB (0.79) | GZMB | |
| SCHEMBL9905055 | 0.88 | GZMB (0.60) | GZMB | |
| SCHEMBL9905018 | 0.88 | GZMB (0.64) | GZMB | |
| SCHEMBL16053005 | 0.87 | GZMB (0.60) | GZMB | |
| SCHEMBL9905088 | 0.87 | GZMB (0.58) | GZMB | |
| SCHEMBL16052769 | 0.87 | GZMB (0.60) | GZMB | |
| SCHEMBL9904999 | 0.87 | GZMB (0.60) | GZMB | |
| SCHEMBL9905011 | 0.86 | GZMB (0.69) | GZMB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139014-A1 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY AND VASCULAR PERMEABILITY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-09-18 | — | — | WO | claimed |
| EP-2648735-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | The University Of British Columbia (CA) | 2013-10-16 | — | — | EP | claimed |
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | claimed |
| WO-2014139014-A1 | METHODS AND COMPOSITIONS FOR THE INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY AND VASCULAR PERMEABILITY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-09-18 | — | — | WO | disclosed |